![]() For example, some forms labeled as keratoconus-suspect in the 1990s would now be described as early forms of clinical keratoconus (Fig. Early diagnosis of subclinical keratoconus therefore depends on the technology used to obtain topographic data. Subclinical keratoconus is a topographic diagnosis: forme fruste keratoconus constitutes the earliest form of subclinical keratoconus it cannot be detected by automated Placido topography and requires analysis of posterior corneal topography and corneal wall thickness variations. We have proposed generalizing the term “subclinical keratoconus” to all corneas in which the phenotypic expression of keratoconus is sufficiently minor to remain asymptomatic. Since then, terms such as “subclinical keratoconus,” “keratoconus-suspect,” and “forme fruste keratoconus,” have been commonly and interchangeably used to describe early forms of keratoconus or forms sharing certain minor features of keratoconus. The introduction of computerized corneal topography subsequently demonstrated the existence of a continuum between the examinations obtained in normal subjects and those with keratoconus.
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